
The A&C Bio Buffer GMP buffer and chemical blend portfolio includes over 50 products, the majority of which are custom blends, solutions or dilutions made under GMP conditions in our new state of the art facility in Limerick, Ireland and our head office in Montreal, Canada. Through the combination of our new GMP manufacturing facility, robust quality management systems, manufacturing expertise and technical excellence, A&C Bio Buffer is a perfect global cGMP partner for custom buffers & custom chemical blends.
WHAT WE PROVIDE
Product Types
- Caustic solutions of ammonium hydroxide, potassium hydroxide, and sodium hydroxide
- Cleaning Solutions
- Phosphate Buffer solutions (PBS)
- Salt solutions of almost any water-soluble salt including sodium chloride and potassium phosphate
- Solvent blends
- Acid blends, such as mixed acid etchants; and dilutions of acetic, citric, hydrochloric, hydrofluoric, phosphoric, sulfuric, and nitric acids.
- Acid/solvent blends, such as nitric acid in methanol
Manufacturing Capabilities
- Multi-compendial
- Robust supply chain traceability and transparency
- Easy second source qualification
- Suitable for use as raw materials and excipients in drug manufacturing applications
- GMP-manufactured products

NEED A CUSTOM BLEND?
To formulate a custom blend or custom buffer, or to outsource your buffer manufacturing to A&C Bio Buffer, please contact us .
product capabilities
A&C Bio Buffer products can meet and are tested against a variety of monographs. Please let us know what grade material you require (USP, Ph. Eur., JP or Pharma grade).A&C Bio Buffer manufacture all our buffers with either USP water or Water for Injection (WFI) water and multi-compendial starting raw materials are used where possible.
If you require a Custom solution, please contact a member of our technical sales team.
We can provide made to-order WFI for further processing in custom packaging options to fit your application. When you are looking for high quality water for cell culture work, in start-up mode with your bio processor, or for cleaning your core, we offer ready to use, cost effective WFI options.
Our Water for Injection (WFI) systems meet both USP and European Pharmacopoeia (EP) standards.
Recommendations:
- Hydration of media, supplements and salt solutions.
- Rinsing of primary packaging, production vessels, equipment and room surfaces.
- Reconstitution and rehydration of product during synthesis.
- Preparation of rinse, purification, and chromatography buffers.
- Further manufacturing of finished product.
PRODUCT
Sodium Chloride |
Sodium Hydroxide |
Sodium Citrate, Dihydrate |
Sodium Phosphate, Monobasic Monohydrate |
Sodium Phosphate, Dibasic Heptahydrate |
Sodium Acetate, Trihydrate |
Citric Acid, Monohydrate |
GRADE
Multi-compendial |
Multi-compendial |
Multi-compendial |
Multi-compendial |
Multi-compendial |
Multi-compendial |
Multi-compendial |
PACKAGE SIZE
Customer batch specific pack size |
Customer batch specific pack size |
Customer batch specific pack size |
Customer batch specific pack size |
Customer batch specific pack size |
Customer batch specific pack size |
Customer batch specific pack size |
PRODUCT
Ammonium Sulfate, NF |
Ammonium Sulfate 38% Solution |
Guanidine Hydrochloride |
Guanidine Hydrochloride 6M Solution |
MES, Monohydrate |
TRIS (Tromethamine), USP, EP |
TRIS Hydrochloride |
Urea |
GRADE
NF |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Reagent |
USP, PH. Eur |
PACKAGE SIZE
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Biological buffers are used in upstream and downstream applications for maintaining pH and protein stability, protein solubilisation and refolding, and column cleaning. A&C’s Products are cGMP-manufactured and compendial biological buffers with full supply chain transparency, no detectable enzymes, low heavy metal content, and low insoluble.
PRODUCT
Sodium Hydroxide, 0.5 N |
Sodium Hydroxide, 1 N |
Sodium Hydroxide, 5 N |
Sodium Hydroxide, 10 N |
Sodium Hydroxide, 25% |
Sodium Hydroxide, 50% |
GRADE
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
PRODUCT SIZES
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
PRODUCT
Acetic Acid, 0.1 N |
Acetic Acid, 1 M |
Acetic Acid, 4 N |
Acetic Acid, 50% |
Acetic Acid, 80% |
Citric Acid, 10% |
Citric Acid, 50% |
Hydrochloric Acid, 0.1 N |
Hydrochloric Acid, 0.24 N |
Hydrochloric Acid, 0.5 N |
Hydrochloric Acid, 1.0 N |
Hydrochloric Acid, 4% |
Hydrochloric Acid, 2.0 N |
Hydrochloric Acid, 3.0 N |
Hydrochloric Acid, 6.0 N |
Nitric Acid, 1% w/v |
Nitric Acid, 16% |
Sulfuric Acid, 1.0 N |
Sulfuric Acid, 2.0 N |
Sulfuric Acid, 4.5 N |
Sulfuric Acid, 5.0 N |
Sulfuric Acid, 10.0 N |
Sulfuric Acid, 45% |
PRODUCT NUMBER
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
GMP Pharma grade |
PACKAGE SIZES
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Bbatch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |
Batch specific packaging available |

Every product we manufacture is backed by the expertise of our professional customer service, technical service and field representatives. Our staff has been trained to meet your service needs whether they are in custom packaging, specialized delivery, follow-up or consulting. We will help our clients match their formulations with the packaging they need to fit their unique system. We can also aid in addressing our client’s specific inventory needs and issues. From the time of purchase to the day of shipment, our team will fully support our clients and their product.
CONTACT A&C BIO BUFFER